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KMID : 1101420190510020191
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Korean Journal of Clinical Laboratory Science
2019 Volume.51 No. 2 p.191 ~ p.197
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Comparison for the Optimal Pressure between Manual CPAP and APAP Titration with Obstructive Sleep Apnea Patients
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Kim Dae-Jin
Choi Byoung-Geol
Cho Jae-Wook
Mun Sue-Jean
Lee Min-Woo
Kim Hyun-Woo
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Abstract
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Although auto-adjusting positive airway pressure (APAP) titration at home has several advantages over a CPAP titration in terms of convenience and time saving, there are still concerns as to whether it will show corresponding accuracy when compared to laboratory-based polysomnography (PSG) and CPAP titration. To obtain more evidence supporting home-based auto-titration, APAP titration was performed at home for patients who were presented with OSA on laboratory-based diagnostic PSG followed by CPAP titration. A total of 79 patients were included in the study. They all underwent split-night PSG with CPAP titration, and APAP titration for more than 7 days. The patients with successful titration at both situations were selected. The optimal pressure and apnea-hypopnea index (AHI) of CPAP and APAP titration were compared. The optimal pressure for CPAP and APAP titration were 7.0±1.8 cmH2O and 7.6±1.6 cmH2O (P<0.001), whereas the corresponding AHI were 1.3±1.5/h and 3.0±1.7/h (P<0.001). As a result, the achievement rates of optimal pressure for CPAP and APAP titration were 96.2% and 94.9% (r=-0.045, P=0.688), respectively. The results of this study did not differ with regard to the optimal pressure between CPAP and APAP titration. Overall, CPAP and APAP titrations should be chosen depending on a required situation.
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KEYWORD
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Apnea-hypopnea index, Auto adjusting positive airway pressure, Continuous positive airway pressure, Hypopnea, Obstructive sleep apnea
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